2026 College Football Odds: USC Favored in Week 0

The 2026 college football season kicks off with Week 0 games that have generated significant betting interest. No. 14 USC is heavily favored against San Jose State, with experts predicting the Trojans will exceed their team total of 48.5 points, potentially scoring seven touchdowns or more. USC has a history of high-scoring performances against similar opponents in recent years.

In Dublin, North Carolina and TCU face off in a rematch of last year's season opener. Betting analysts suggest the Under 47.5 points due to expected rain and wind, plus question marks surrounding both teams' new starting quarterbacks. Meanwhile, NC State visits Virginia in what's expected to be a close game, with the Wolfpack favored to cover the spread after winning last year's meeting 35-31. amunra.qpon